ISEH 2020 Award Winners
On behalf of the Awards Committee, ISEH would like to congratulate the recipients of the 2020 ISEH Honorific Awards, which will be presented at the ISEH 2020 Virtual Scientific Meeting:
2020 Donald Metcalf Award Winner: Harvey Lodish
Recent work in Harvey’s group focused on characterizing novel genes important for the terminal stages of erythropoiesis, including chromatin condensation and enucleation, as well as the regulation of self-renewal, proliferation, and differentiation of erythroid progenitor cells by glucocorticoids and oxygen.
"Dr. Lodish’s illustrious scientific career spanning several decades and his broad scientific impact - exploring plasma membrane proteins, receptors, iron transporters, adipogenesis, Hematopoiesis- have been previously recognized by a number of Awards/distinctions (i.e member of NAS, of AAAS, of AAM, etc.). An additional remarkable feature in his career is the mentoring of 175 students/mentees-two of them winning the Nobel prize (2004 and 2013) and Lasker Awards and many holding leadership positions in other major Institutions (Dr. Lodish was the Recipient of Basic Science Mentor Award by ASH, 2010).
Our Society, ISEH, is proudly bestowing its highest award, the Metcalf Award, to Dr. Lodish by recognizing and rewarding his exceptional and steady contributions - identifying molecular pathways, molecules, transcriptional factors, LncRNAs, etc. - in Hematopoiesis and especially in Erythropoiesis." – Thalia Papayannopoulou, MD, Dr Sci, Elo Giblett Endowed Chair, University of Washington
2020 McCulloch & Till Award Winner: Mark Dawson
“Dr. Dawson has been an absolute pioneer in our understanding of how epigenetic regulators contribute to the initiation, maintenance, and progression of acute myeloid leukemia and other aggressive hematological malignancies. His groundbreaking scientific discoveries have led to the characterization of novel epigenetic mechanisms as well as the development of epigenetically-targeted therapies which have been translated from the laboratory into the clinic. As an active physician scientist, he has also led several of these clinical trials and leveraged larger international translational collaborations to study and decipher molecular mechanisms that underlie response and resistance to epigenetic therapies. In this context, I would like to particularly highlight Dr. Dawson’s pioneering work on non-genetic mechanisms of therapeutic resistance, the impact of which is hard to overstate, and which has moved the entire field into a novel direction, which is now explored by numerous laboratories around the globe. I cannot think of a more innovative, impactful, and deserving scientist to receive this prestigious award.” – Ulrich Steidl, MD, PhD, Albert Einstein College of Medicine
2020 Janet Rowley Award Winner: Jennifer Trowbridge
“I am beyond excited that ISEH is awarding the inaugural Janet Rowley Award to a most deserving shining star in our field, Dr. Jennifer Trowbridge. Dr. Trowbridge already had an exceptional track record in discovering novel regulatory mechanisms that govern HSC fate decisions during her graduate studies in Mickie Bhatia’s lab and post-doctoral training with Stu Orkin. In her own lab, she is leveraging her unique expertise in chromatin biology to uncover the mechanisms that go awry during ageing or malignant transformation. Her innovative and rigorous work has already resulted in several landmark papers that are changing our understanding of the ageing process and clonal hematopoiesis. Her work has been celebrated by prestigious scholar awards (ASH Scholar, V-foundation Scholar, Ellison Medical Foundation New Scholar in Ageing, Evans MDS Discovery Research grant) and highly praised presentations at meetings, including the selection of her postdoc’s abstract in the highly coveted and extremely competitive Plenary Session in the American Society of Hematology annual meeting last year. Seeing her trainees give these impressive presentations in major meetings is a testament to the fact that Dr. Trowbridge is a fantastic mentor. Dr. Trowbridge is also shaping the field through serving in hematology societies, and by being a generous collaborator whose model systems will have an impact for many years to come. She truly embodies the same attributes as Dr. Janet Rowley, by being an influential scientist and an inspiring role model.” – Hanna Mikkola, MD, PhD, Eli and Edythe Broad Stem Cell Research Center, University of California Los Angeles