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Showing posts from 2021

Lab Spotlight: The Van Galen Lab

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Each month, Simply Blood spotlights a lab focused on the research of basic hematology, immunology, stem cell research, cell and gene therapy, and other related aspects. Get to know these different labs around the world! This month, we are featuring the Van Galen Lab at the Division of Hematology, Brigham and Women’s Hospital and Harvard Medical School located in Boston, MA, USA! How long have you had your lab? We started in August 2019. How many members make up your lab? Students/postdocs? There are currently six trainees. We have two postdocs, two technicians, a visiting PhD student and a part-time undergraduate student. What is the major research theme of your lab? In the broadest sense we focus on normal and malignant hematopoiesis. We develop and apply new technologies to study the process of hematopoietic stem cell (HSC) differentiation in human cells. A molecular understanding of changes that occur during aging and transformation of the blood system will inspire new therapies tha

Message from the President: Introducing the Paul S. Frenette Fund

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The ISEH community is deeply saddened by the recent loss of Dr. Paul Frenette, a revered member of the ISEH community and ISEH Past President. In order to honor and memorialize Dr. Paul Frenette in a long-lasting way, ISEH is in the process of launching the “Paul S. Frenette Fund”. The “Paul S. Frenette Fund” will be designed as an endowment, with a goal that its annual proceeds will be applied to generate an annual named “Paul S. Frenette Lecture” at the ISEH Annual Scientific Meeting, as well as towards travel grants in honor of Paul. These travel grants and lectures may be selected thematically, such as contributions submitted related to niche biology or sickle cell disease, or pioneering and visionary research in general that may be ahead of its time. If you would like to contribute to the “Paul S. Frenette Fund” or learn more, please visit the ISEH website at https://www.iseh.org/page/frenettefund . ISEH is a registered 501(c)3 organization in United States of America. ISEH will c

ISEH 2021 Annual Scientific Meeting - Final Thoughts

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Before writing the ISEH 2021 Virtual Scientific Meeting recap, we had a quick read-through of last year’s summary. One year ago, we were hoping that our first virtual ISEH meeting would also be our last. We couldn’t wait to see each other again in person, and this is still the case. We are now hopeful that the ISEH 2021 Virtual Scientific Meeting will be our last fully virtual meeting. Travel is becoming more realistic with increasing COVID vaccination rates, so we are already looking forward to meeting in-person in Edinburgh in 2022. One major advancement since last year: we have become experts at meeting virtually. Thanks to the hard work and contributions of many people, we had a fantastic Virtual Meeting for ISEH 2021! The science was ground-breaking, the speakers were excellent, the networking events were fun, and the educational sessions were, well, extremely educational. Here is a recap of what happened at the ISEH 50th Annual Scientific Meeting. Registration Firstly, let’s sta

ISEH 2021 New Investigator Awards

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Our society takes great pride in supporting the work of young scientists who submit cutting-edge abstracts for discussion at the ISEH Annual Meeting. To this end, each year ISEH includes a New Investigator Session in which the Program Committee selects the six highest ranked abstracts to present an oral presentation along with a five minute Q&A. Presenters were reviewed by an anonymous panel of judges on the following criteria: presentation topic, presentation content, Q&A response, and overall presentation. The session awards prizes into two groups – student and postdoctoral fellow, with three prizes being awarded in each category. Congratulations to our 2021 New Investigator Award Winners! Students 1st Place Prize - Dirk van Bekkum Award Bianca Ulloa Albert Einstein College of Medicine, USA Definitive Hematopoietic Stem Cells Minimally Contribute to Embryonic Hematopoiesis 2nd Place Prize - T. Ray Bradley Award Emily Mitchell Wellcome Sanger Institute, UK Haematopoietic stem

Thank You to our 2021 ISEH Scientific Meeting Sponsors and Supporters

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    The ISEH Annual Meeting looks a bit different again this year. We're celebrating 50 years of our scientific meeting with an exciting program including career and technology sessions, as well as talks and poster presentations from trainees, new investigators and leaders in the field. On behalf of the ISEH Board of Directors, volunteers, and staff, we'd like to thank our 2021 sponsors and exhibitors, seen below. We hope to see you all in Edinburgh, Scotland, UK in 2022! Support for ISEH 2021 provided by: An independent medical education grant by Bristol-Myers Squibb. A grant from Genentech, a member of the Roche Group. A grant award from the National Institute Of Diabetes And Digestive And Kidney Diseases of the National Institutes of Health. THANK YOU TO OUR 2021 PLATINUM SPONSORS THANK YOU TO OUR 2021 GOLD SPONSORS THANK YOU TO OUR 2021 SILVER SPONSORS THANK YOU TO OUR SUPPORTERS THANK YOU TO OUR EXHIBITORS  The views expressed in written conference materials or publi

President's Message: Welcome to ISEH 2021!

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On behalf of ISEH, the International Society for Experimental Hematology, I would like to thank you for being a part of ISEH 2021. This year we begin the celebration of 50 years of unparalleled science as coalesced around a professional society and annual international meeting. While we are not able to meet in person in 2021, we hope that this virtual meeting provides an opportunity for you to re-connect with science and colleagues from around the world.    Through a combination of invited keynote speakers and oral presentations, the ISEH meeting boasts educational sessions on basic, translational and clinical hematology featuring internationally-renowned scientists as well as rising young investigators.  Presenting cutting-edge research is only one of the features of the Annual Meeting. To maximize presentations and audience engagement, we again continue the sessions we started last year called “Featured Posters.” These lightning talks to advertise posters again promise to be brillian

In Memory of Paul Sylvain Frenette

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The ISEH community is deeply saddened by the recent loss of Dr. Paul Frenette, the founding director and chair of the Ruth L. and David S. Gottesman Institute for Stem Cell Biology and Regenerative Medicine Research at Albert Einstein College of Medicine. Paul was a revered member of the ISEH community, having previously served as President in 2015 in addition to other leadership positions. Our deepest condolences extend to his family, colleagues at Einstein, and collaborators around the world who are suffering from this loss. More details about Paul’s remarkable career and scientific accomplishments can be found in an obituary in Experimental Hematology ( https://www.exphem.org/article/S0301-472X(21)00282-4/fulltext ). To accompany that piece, in this Simply Blood blog please find some additional testimonies and pictures. Dr. Meelad Dawlaty, Associate Professor, Albert Einstein College of Medicine. “Paul was always there for his trainees, staff and fellow faculty like a friend. As

How To: Network at Virtual Conferences

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With Covid-19 came the widespread introduction of virtual conferences. While there are obvious advantages to virtual conferences including saving time and money on travel and increasing content accessibility to a larger and more diverse science community, this has come at a cost of decreased networking and less face-to-face interactions. are necessarily limited. This is particularly relevant for Poster presentation sessions, which are usually a hub for networking but now mostly occur through short, pre-recorded summaries with no actual discussion taking place. While solutions to the problem of networking vary from conference to conference, below are some general tips on how to still get the networking you enjoy out of virtual events. Come prepared As always, preparation is key. Scan the programme, abstracts and participant list for people you might want to connect with. Read up on their research to assess which sessions of the conference they will likely attend.  It is also useful to p

2021 Interview Spotlight Series: Part IV

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This week on Simply Blood we close out our 2021 Interview Spotlight Series! Part IV features the ISEH 2021 Donald Metcalf Award Winner:  Tony Green, Ph.D . Click below to listen as Dr. Green answers questions about his scientific passions, career path, mentorship and more. Interested in hearing more about Dr. Green's fascinating work?  Don’t miss his session at this year’s ISEH Virtual Scientific Meeting ! Tony Green, PhD Director, Wellcome-MRC Cabridge Stem Cell Institute Professor, Haematopoiesis and Myeloid Malignancies Cambridge Stem Cell Institute University of Cambridge stemcells.cam.ac.uk/people/pi/green Interviewed by Stephen Loughran of the  ISEH New Investigators Committee

2021 Interview Spotlight Series: Part III

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This week on Simply Blood we continue our 2021 Interview Spotlight Series! Part III features the ISEH 2021 McCulloch & Till Award Winner:  Camilla Forsberg, Ph.D . Click below to listen as Dr. Forsberg answers questions about her scientific passions, career path, mentorship and more. Interested in hearing more about Dr. Forsberg's fascinating work?  Don’t miss her session at this year’s ISEH Virtual Scientific Meeting ! Camilla Forsberg, PhD Director, Institute for the Biology of Stem Cells Professor of Biomolecular Engineering University of California Santa Cruz forsberglab.soe.ucsc.edu/ Interviewed by Camille Malouf of the  ISEH New Investigators Committee

2021 Interview Spotlight Series: Part II

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This week on Simply Blood we continue our 2021 Interview Spotlight Series! In Part II we are highlighting the ISEH 2021 Janet Rowley Award Winner: Elisa Laurenti, Ph.D . Click below to listen as Dr. Laurenti answers questions about her scientific passions, career path, mentorship and more. Interested in hearing more about Dr. Laurenti’s fascinating work?  Don’t miss her session at this year’s ISEH Virtual Scientific Meeting ! Dr Elisa Laurenti Sir Henry Dale Fellow - Group Leader Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute Centre for Haematopoiesis and Leukemia Research - Department of Haematology - University of Cambridge Jeffrey Cheah Biomedical Centre Cambridge Biomedical Campus www.stemcells.cam.ac.uk Interviewed by Myriam Haltalli  ISEH New Investigators Committee  & Kellie Machlus of the ISEH Junior PI Committee

Lab Spotlight: The Velten Lab

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Each month, Simply Blood spotlights a lab focused on the research of basic hematology, immunology, stem cell research, cell and gene therapy, and other related aspects. Get to know these different labs around the world! This month, we are featuring the Velten Lab at the Centre for Genomic Regulation located in Barcelona, Spain! How long have you had your lab? I only started in January 2020. There was a pandemic for almost 90% of the time that my lab has existed… Fortunately, the Spanish anti-Corona measures were only really tough for three months. So, despite everything, we were able to grow together as a team and get experimental work done. What was your biggest transition from a post-doc to a group leader/lab PI? To me, it felt like a big relief. As a senior postdoc, I was leading or co-leading three projects and was involved in even more. The number of projects I’m involved in is definitely not getting smaller, but now I can strategically grow a team of independent and dedicated res

2021 Interview Spotlight Series: Part I

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This week on Simply Blood we are kicking off our 2021 Interview Spotlight Series. In Part I we are featuring the ISEH 2021 New Investigator’s Invitee: Dan Landau, M.D, Ph.D. Here, Dr. Landau answers questions about his scientific passions, unusual but highly successful career path, mentorship and more. Interested in hearing more about Dr. Landau’s fascinating work? Don’t miss his session at this year’s ISEH Virtual Scientific Meeting ! 1. What is your key scientific question? What do you consider as your major contribution to the field over the past 5 years? The lab’s key scientific question is exploring the fundamental principles of human somatic evolution. We are fascinated by the realization that the trillions of cells in our body continuously evolve throughout life, with significant implication to human health and disease. Cancer represents an extreme case of human somatic evolution where in a “runaway process” cells evolve more rapidly at the expense of the multi-cellular host. O

COVID-19 Lockdown Effects on Research in Melbourne

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Australia has been relatively lucky in the current pandemic because, to date, we have managed to eliminate community transmissions of COVID. We did, however, experience significant community transmission in Melbourne (and some other parts of Australia) in 2020. The people of Melbourne (a city of approximately 5 million people) were subjected to strict lockdowns that has, fortunately, been successful. I have been asked to give a first-hand account of the local situation and the impact on researchers in Melbourne. Our first lockdown commenced on 24th March. Social distancing measures were put in place everywhere. We were permitted to leave our homes for 2 hours daily for exercise and shopping, although it was advised to limit shopping and preferably only have one household member do the shopping. Our second, harsh lockdown commenced on 9th July and continued through the end of October. We were allowed one hour of exercise outside per day (restricted to a 5km limit) and only one household