simply blood

The 2024 NIC at the ISEH 53rd Annual Scientific Meeting Don't Miss the New Investigator Committee Sessions in Kumamoto! Are you a trainee who will attend the ISEH 2025 Annual Scientific Meeting in Kumamoto? If so, you need to check out the educational and career sessions organized by the New Investigator Committee (NIC). It is a great opportunity to meet trainees from around the world and to network with PIs and core members of the ISEH. Forming new bridges with them will benefit your scientific career and open doors to new collaborations. Here is a breakdown of our sessions that can be added to your meeting registration. New Investigator Pre-Meeting Workshop (PMW) Are you an early career researcher (student or postdoc) looking to connect with peers and mentors, receive feedback on your poster, and get an opportunity to present your work at the ISEH 2025 annual meeting? Look no further than the New Investigator Pre-Meeting Workshop (PMW)!  The PMW will be held on the afternoon of S...

Welcome to another episode of our long-running Preprint Watch series! If you are preparing your return to the lab, these preprints will definitely help you out, catching some of the most exciting research in the field of experimental hematology! This month, we have two submissions from our community - one from the Erasmus Medical Center in the Netherlands and another from the University of Cambridge, UK, in which we were able to have a lovely chat with one of the first authors, Dr. Zarocsinceva.  If you want to see your research featured here, please send it through this form:  https://www.iseh.org/page/Preprints .  From the Simply Blood Community: Targeting mitochondria mitigates chemotherapy-induced bone marrow dysfunction https://www.biorxiv.org/content/10.1101/2025.07.18.665515v1?rss=1 Herein, the authors have shown that 5-FU chemotherapy induces long-term damage to HSCs that resembles premature ageing and is driven by persistently altered mitochondrial metabolism. Tr...

Derecka Lab Each month, Simply Blood spotlights a lab contributing to the fields of hematology, immunology, stem cell research, cell and gene therapies, and more. Get to know groups doing cutting edge research from around the world! This month, we are featuring the Derecka Lab out of St. Jude Children's Research Hospital, USA.  How long have you had your lab?   I started in November 2020, so it’s almost 5 years. Time flies, really.  How many members make up your lab?  Currently, we are 5 people: I have one postdoc, a scientist, a research technician, an undergraduate student, and me. What is the major research theme of your lab? We are trying to understand how bone marrow microenvironment affects hematopoiesis at steady state and blood malignancies. We have a very specific interest in identifying key transcription factors regulating stromal cells biology.   What is the most exciting project in your lab right now? That’s a tricky question since I think...

This week on Simply Blood, we are delighted to share an inspiring conversation with Dr. Toshio Suda, the Editor-in-Chief of Experimental Hematology ( ExphHem )! As an ISEH Board of Director, Chief Associate Editor of ExpHem , and a liaison to the ISEH Publication Committee, Dr. Keisuke Ito from Albert Einstein College of Medicine, NY, USA, had the unique opportunity to discuss the journal’s evolution including its future vision, and the ongoing efforts that are shaping the field of experimental hematology. Panel 1. 1.      What inspired you to become an editor, and why did you choose Experimental Hematology among many journals? My first experience with ISEH was at the 8th Rotterdam Annual Meeting, where I presented a poster on the immunological aspects of aplastic anemia. Interestingly, I was standing next to a young researcher from Switzerland giving a similar presentation—that was a real eye-opener, making me realize how interconnected our global community truly is. O...

Read the highlights from  Inhibitory effects of SARS-CoV-2 spike protein and BNT162b2 vaccine on erythropoietin-induced globin gene expression in erythroid precursor cells from patients with β-thalassemia   by Lucia Carmela Cosenza, Giovanni Marzaro, Matteo Zurlo, Jessica Gasparello, Cristina Zuccato, Alessia Finotti, and Roberto Gambari In this issue of Simply Blood, we are highlighting a manuscript led by first author Lucia Carmela Cosenza conducted in the laboratory of Dr. Roberto Gambari at the Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy. This is the first study to demonstrate that both the SARS-CoV-2 spike (S) protein and BNT162b2 mRNA vaccine can inhibit fetal hemoglobin (HbF) production by and reduce γ-globin mRNA accumulation in β-thalassemic erythroid precursor cells (ErPCs). Despite widespread vaccination efforts, COVID-19 remains a global health challenge. Emerging research suggests that the SARS-CoV-2 S-protein may contribut...