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Preprints: How To Advance Your Research!

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The pace of science is accelerating. Papers are becoming ever more interdisciplinary and complex, and the revision process is turning more and more arduous. As jobs become more competitive, the pressure to publish in top impact journals keeps getting higher. The result of all this is that high quality submissions are suffering from unacceptably long publishing queues, which negatively impacts the dissemination of important results. To accelerate the speed at which important findings are shared with the global scientific community, researchers in physics, economics, mathematics and computer sciences have long used the preprint model. This involves depositing a finished manuscript in an open access preprint server for the community to interpret, judge and ultimately learn from. The server operators minimally check the manuscript for appropriate content, but do not judge or peer-review the science. Thus, a preprint does not substitute for properly peer-reviewed research in an indexed jou
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Exploring Experimental Hematology: November 2020 (Volume 42)

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In this issue of Simply Blood , we are deconstructing an invited perspective from Experimental Hematology as  Dr. Forsberg and colleagues build on their interesting prior work on differentiation of tissue resident macrophages (trMacs) via an interleukin-7 a   receptor (IL7R a )-positive progenitor (Leung et al. 2019). trMac differentiation follows a ‘nontraditional’ pathway of myeloid cell specification occurring in fetal hematopoiesis. In this study, they now examine the role of IL-7 signaling in the maintenance of other tissue myeloid cells - neutrophils and eosinophils - in the lung, work directed at better understanding the immune system of the lung and its relationship to respiratory diseases. First, the authors examined lung B-cell, neutrophil, and eosinophil content in Flk2 -/- , IL7R a -/- , or combined knock-out mice. Dr. Forsberg had previously shown that all ‘traditional’ adult myeloid and lymphoid cells, but not trMacs, develop via a Flk2-positive progenitor (Beaudin et
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Becoming Your Best Advocate

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What is self-advocacy? Self-advocacy involves speaking up for yourself, your worth, and your needs. The concept of self-advocacy transcends disciplines and its’ mastery is critical for the career development and promotion of scientists at all stages of training. Self-advocacy requires you to bring attention to yourself and your needs, which may be a particularly uncomfortable task for trainees from disadvantaged backgrounds. Under-represented minority scientists are often the only person from a particular background in their group, department, or institution, and thus they may not feel a strong sense of support in their current position. Unfortunately, under-represented minority scholars often feel as though they are responsible for carrying the weight of their communities as they complete their training, and this will not be corrected until dedicated efforts are put forth by the scientific community to support diversity and inclusion. For example, under-represented minority scientist
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ISEH 2020 Virtual Scientific Meeting - Final Thoughts

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We survived our first virtual ISEH meeting - our first, and hopefully our last! I'm sure it is safe to say that everyone missed the comradery and personal experience that is typical in an ISEH meeting, but as far as virtual meetings go, this one was as close as we could come to re-creating the real thing. Now that the ISEH 2020 Virtual Scientific Meeting has concluded, we thought it would be a good time to reflect on the overall experience. To start off, we'd like to share with you a breakdown of a few features and demographics from the meeting: Registration There were 527 registered participants in the virtual meeting. This is including speakers, exhibitors, sponsors and paid attendees. Our attendees logged in from all over the world with 30% from Europe/Middle East/Africa, 61% from the Americas, and 9% from Asia/Pacific Rim. These attendees represented 28 different countries! Engagement Over the course of the live meeting we had:  654 private messages sent among attendees 2,0
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Exploring Experimental Hematology: August 2020 (Volume 88)

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In this issue of Simply Blood, we are highlighting and deconstructing an invited perspective from the latest Experimental Hematology, "Lineage commitment of hematopoietic stem cells and progenitors: insights from recent single-cell and lineage tracing technologies" by Loughran et al. This perspective summarizes the Summer 2019 ISEH New Investigator Committee Webinar, "Changing concepts in lineage commitment" and update the recent progress of understanding lineage commitment using lineage tracing combined with single-cell transcriptomics and proteomics. ( Loughran et al., 2020 ) My reason to read this paper: The self-renewal and multilineage differentiation abilities are two essential characteristics of hematopoietic stem cells (HSCs). In the history of the hematopoietic field, to understand the cell fate determination and lineage potential from each HSC and progenitor population, people have taken various strategies including colony-forming assays, stromal co-cultur
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Thank You 2020 Sponsors and Exhibitors!

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  The ISEH Annual Meeting looked a bit different this year. We celebrated the 2020 Virtual Scientific Meeting with our exciting program including career and technology sessions, as well as talks and poster presentations from trainees, new investigators and leaders in the field. On behalf of the ISEH Board of Directors, volunteers, and staff, we'd like to thank our 2020 sponsors and exhibitors, seen below. We hope to see you all in New York in 2021! This program is supported by an independent medical education grant by Celgene Corporation. THANK YOU TO OUR 2020 GOLD SPONSOR THANK YOU TO OUR 2020 SILVER SPONSORS THANK YOU TO OUR 2020 BRONZE SPONSORS THANK YOU TO OUR SUPPORTERS Funding for this conference was made possible (in part) by 1R13HL154589-01 from the National Heart, Lung and Blood Institute. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the NIH; nor does mention by trade
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2020 Award Winner Spotlight Series: Part IV

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This week on Simply Blood we are wrapping up our 2020 Interview Spotlight Series. In Part IV we are featuring the 2020 ISEH Donald Metcalf Award Winner: Harvey Lodish, MD . Here, he answers questions about his life, work, mentorship, and more. Have additional questions for Dr. Lodish? Don't miss his opening Keynote session at this year’s Virtual Scientific Meeting !
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