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Showing posts from 2018

Lab Spotlight: Perie Lab

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Each month, Simply Blood spotlights a lab focused on the research of basic hematology, immunology, stem cell research, cell and gene therapy, and other related aspects.  Get to know these different labs around the world! This month, we are featuring the Perié Lab at the Curie Institute in Paris (France).



Leïla Perié works as a principal investigator in the biophysics department of the Curie Institute in Paris (France). Her research combines advanced experimental cell tracking techniques and modeling to study hematopoiesis. She received an engineering degree in food science, as well as a PhD in experimental immunology, bringing new insight to immune cell geo-localization dynamics in the human spleen during HIV infection. Leïla then pursued postdoctoral training in experimental, computation and mathematical approaches to hematopoiesis funded by a European Marie Curie Fellowship. She was sharing her time between the Schumacher lab at NKI (Amsterdam) and the De Boer lab at Utrecht Univers…

The Sandwich Effect

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I guess we have all eaten sandwiches. Personally, I have a love-hate relationship with them. They can be tasty, healthy, diverse, and most of all easy and effortless to make. They can also be extremely messy while you are eating them. This is because of quirky fact about sandwiches: I always associate them with PRESSURE. Because, if you think about it, there are roughly three parts on a sandwich: a slice of bread, the stuffing and another slice of bread. A sandwich is basically a handheld mini-pressure machine. It is almost certain that if you put pressure on one of the parts, the pressure will be transferred to the other parts. There is no other way to eat it- unless you disassemble the sandwich, but then the advantages of the sandwich are lost. By now you might be thinking you are reading a foodie blog, but the point of this blog is not the food but how the sandwich reminds me of the current paradigm for academic science. Each step in our careers can be considered part of the sandw…

How to Make Scientific Writing Easier

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We have all felt the inertia when we need to write – whether it’s an abstract, paper, report or grant – and it can feel daunting and hard to get started. We feel like we need a big slot of time, or we need to have all the conditions just right (if you are anything like me - quiet, a cup of tea, and tidy desk) or that there’s just one more experiment that we need to complete before we sit down and begin.    

And, what happens when we do not get started? We lose the momentum of our greatest ideas. We end up working closer to deadlines and under pressure, which may not create our best work.  Or worse, if there’s no deadline (for example, when you are writing a paper), we end up putting it off and suddenly we’ve been scooped, or the data has lost its vitality.

During my 15 years of organizing, editing and developing grants with leading scientists, I have learned that writing is a process. Learning how we approach writing and the roadblocks that come up for us has captivated me and I ha…

Lab Spotlight: Passegué Lab

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Each month, Simply Blood spotlights a lab focused on the research of basic hematology, immunology, stem cell research, cell and gene therapy, and other related aspects.  Get to know these different labs around the world! This month, we are featuring the Passegué Lab at Columbia University in New York City, USA.


How long have you had your lab?
I got officially hired by the University of California, San Francisco (UCSF) in December 2005, but I didn’t hire my first lab member until March 2006. My lab relocated to Columbia University in New York City last year.

How many members make up your lab? Students/postdocs?
Since the relocation, my lab consists of 4 postdocs, 1 MD/PhD fellow, 1 graduate student, 1 lab manager and a junior tech, as well as a number rotating students and interns.

What is the major research theme of your lab?
The big question is regulation of blood production. All the current projects further fit under two axes – 1) emergency myelopoiesis and regenerative processes, an…

Exploring Experimental Hematology: Beyond the Krebs cycle

We are beginning a new blog series on SimplyBlood called “Exploring Experimental Hematology.” Here we will highlight and deconstruct some our favorite manuscripts from the ISEH society journal. Welcome to entry 1.

If you are a millennial or are raising a post-millennial you must be familiar with unboxing YouTube videos where you can watch someone open a new item and then explain the item in detail. While I might not fully understand why my kids enjoy watching other kids open toys, I do get the excitement of sharing my thoughts and deconstructing a new and exciting Experimental Hematology article for the community.

In this blog, I'll be exploring the review “Hematopoietic stem cell fate through metabolic control” by Kyoko Ito and Keisuke Ito.

My reason for reading the paper:
They have provided us with an excellent review on HSC and metabolism that is a must read for anyone in the HSC field. I still remember the first time I heard a Toshio Suda talk about hematopoietic stem cells …

47th Annual Scientific Meeting - Thank you!

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The 47th Annual International Society for Experimental Hematology meeting took place in sunny Los Angeles, California, August 23-26th. The exciting program (https://www.iseh.org/page/2018Program) included career and technology sessions, as well as talks and poster presentations from trainees, new investigators and leaders in the field.


On behalf of the ISEH Board of Directors, volunteers and staff, we'd like to thank our 2018 sponsors and exhibitors, seen below. We hope to see you all in Brisbane in 2019!


Thank you to our 2018 Platinum Sponsors



Thank you to our 2018 Gold Sponsors







Thank you to our 2018 Silver Sponsor



Thank you to our 2018 Educational Support Sponsors


Lab Spotlight: Ding Lab

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Each month, Simply Blood spotlights a lab focused on the research of basic hematology, immunology, stem cell research, cell and gene therapy, and other related aspects.  Get to know these different labs around the world! This month, we are featuring the Ding Lab at Columbia University.


How long have you had your lab?
I started in February 2013. So a little over 5 years.

How many members make up your lab? Students/postdocs?
There are four graduate students and one postdoc in the lab currently. I would like to have another postdoc or two. That will be the ideal composition of my ‘dream’ lab.

What is the major research theme of your lab?
We investigate the molecular and cellular mechanisms, particular extrinsic mechanisms, that regulate hematopoietic stem cell function. We also study how these mechanisms contribute to hematological diseases.

What's your best approach to mentoring students in the lab?
Everyone is different. I try to tailor my mentoring style to each student. The goal …

When do you feel like you have ‘made it’ in academic science?

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A funny thing happened to me the other day – I got the official notice that my promotion to Associate Professor of Medicine with tenure was approved (Washington University School of Medicine, St. Louis).  It was all very anticlimactic, just a letter that showed up in my internal mailbox.  There was no phone call from the Dean or the Chair of the Department of Medicine, no big party, no fanfare – just a signed letter staring back at me.  It was a very surreal experience.  This is something most of us strive for and work so hard towards and then when the moment arrives, it was all very … meh.

Sometimes it still doesn’t seem real, I keep waiting for someone to tap me on the shoulder saying … oops we made a mistake.  I go to meetings and conferences and see all the amazing work being done by my colleagues, contemporaries and collaborators and it’s hard not to feel overwhelmed.  So much of the world’s cutting edge research is being done in hematology that as a young investigator it is rea…

Lab Spotlight: Stachura Lab

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Each month, Simply Blood spotlights a lab focused on the research of basic hematology, immunology, stem cell research, cell and gene therapy, and other related aspects.  Get to know these different labs around the world! This month, we are featuring the Stachura Lab at California State University, Chico.  


How long have you had your lab?  
Since 2014

How many members make up your lab?  Students/postdocs? 
I currently have 12 members; 6 undergraduate students and 6 Master’s students.  I’m at a primarily undergraduate institution, so I don’t have any Ph.D. students or postdocs.  

What is the major research theme of your lab?  
Our major goal is to discover genes essential for hematopoietic stem and progenitor cell differentiation and proliferation, and how this normal process is disrupted in blood diseases.

What is the most exciting project in your lab right now?
We have a few exciting projects going in the lab, and they are pretty diverse.  Some students are looking at anti-cancer drug…

Things Nobody Told Me about Being a PI - Part 3

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Welcome back to the blog series “Things Nobody Told me About Being a PI”.  In part 1, we covered financial/administrative management.  Part 2 dealt with personnel/team management.  In the final installment, I would like to touch on an issue which was a big personal adjustment for me.

Something that was completely unexpected for me as a new PI was a sense of loneliness.  As a post-doc, you are probably used to working in a busy lab, maybe in a bay of 2-3 other trainees all bustling around doing experiments.  This builds a sense of comradery as you bond over failed experiments, talk about exciting new papers, and maybe plan what beers you are going to try at happy hour that afternoon.  As a new PI, you often spend a lot of time alone in your office - writing grants / papers, attending to the masses of incoming email, and handling all your regulatory protocols.  Even though you might be surrounded by people running around in the lab, and even other PIs down the hall, the relative silence …

Lab Spotlight: Trompouki Lab

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Each month, Simply Blood spotlights a lab focused on the research of basic hematology, immunology, stem cell research, cell and gene therapy, and other related aspects.  Get to know these different labs around the world! This month, we are featuring the Trompouki Lab at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany.  


How long have you had your lab?
I have had my lab for four and a half years now. Time flies!

How many members make up your lab?  Students/postdocs?
Right now my lab consists of four graduate students, but one is very close to graduating!! This will be the first student graduating from our lab. We have also a postdoctoral fellow and a technician. Finally, a master student and an intern complete the current composition of our team.

What is the major research theme of your lab?
We are working on hematopoiesis, both developmental and adult, using zebrafish, mouse and human cells as models. A bit too much for a small lab, but we think that each …

Making the Leap, Part 6. Prepare for Landing

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Faculty interviews are over. You’ve negotiated your offers and decided on an institution that fits your needs. Your signed letter has been sent back and (importantly) has been approved by the dean(s) or other institutional heads, making it official. Maybe you’ve made or have scheduled a couple of additional visits to your future scientific home. The end of your post-doctoral training is in sight. Now what? I made my final decision to join the faculty of University of Colorado’s Anschutz Medical Campus in July of 2015, with a planned start date at the beginning of November that year. The intervening time was full of excitement and anticipation, and plenty of work to tie together loose ends in my postdoc and set the stage for my faculty position. Now that you’ve made the leap, here are a few things to consider as you prepare for landing.

1) Celebrate. Don’t overlook this. You’ve worked hard and all of the effort has borne fruit. It’s worth getting your friends, colleagues and mentor(s) …