Posts

Showing posts from January, 2019

Exploring Experimental Hematology: Salad or Burger for Dinner? Your Stem Cells Don't Really Care.

Image
In this issue of Simply Blood, Evgenia Verovskaya is Exploring Experimental Hematology and highlighting and deconstructing one of her favorite manuscripts from the ISEH society journal: "Lifelong dietary intervention does not affect hematopoietic stem cell function" by Seka Lazare et al.

Across the planet, people are living longer and longer. Can we influence how healthy we age? Many studies of organismal aging indicate that healthy diet and exercise can reduce age-related morbidities. But working in the field of blood research, the question is – can dietary choices also prevent aging of hematopoietic stem cells (HSCs), and rejuvenate blood production in the elderly? The group of Gerald de Haan addressed this question using the mouse model and published their interesting findings in Experimental Hematology.


What to expect in this paper:

The de Haan group examined HSC function in C57/BL6 mice fed a high fat, low fat, or calorie-restricted diet throughout their whole life. As …

ISEH January 2019 – Message from the President: Bertie Gottgens

Image
Dear Friends and Colleagues,

I write this message to you in the last few days of December, reflecting on the past year and pondering the year ahead.  Looking back at 2018, a real highlight for me was the 47th annual meeting of the ISEH in LA.  As I see it, our research field of experimental haematology is going through a sustained period of positive growth and momentum.  It is pleasing therefore to see that the ISEH meeting is doing such a fabulous job at capturing this sense of excitement, ranging from breakthroughs in our understanding of the fundamental principles that control blood development, all the way to achieving real clinical impact from the application of new technologies and harnessing the underlying biology.

I firmly believe that one of the main reasons behind ISEH’s ability to capture the excitement in our field is the strong emphasis on, and contribution from, our junior members.  I am delighted to see the continued enthusiasm emanating from our junior investigator c…

Lab Spotlight: Kent Lab

Image
Each month, Simply Blood spotlights a lab focused on the research of basic hematology, immunology, stem cell research, cell and gene therapy, and other related aspects.  Get to know these different labs around the world! This month, we are featuring the Kent Labat the University of Cambridge in the United Kingdom.


About the PI
David Kent earned a B.Sc. in Genetics and English Literature at the University of Western Ontario, Canada (1999-2003). He obtained his Ph.D. in normal adult blood stem cell biology at the University of British Columbia, Canada (2003-2009) under the supervision of Connie Eaves. Then, he moved to the University of Cambridge as a postdoctoral fellow in the lab of Anthony Green, where he primarily studied malignant blood stem cell biology. In 2015, he started his own research group at the University of Cambridge. His group studies fate choice in single blood stem cells and how changes in their regulation lead to cancers.

David is currently the Cambridge Stem Cell Ins…