Posts

Showing posts from April, 2020

COVID 19 Series: Happy Hour Wrap-Up

Image
On April 10th, ISEH hosed a webinar – actually more of a ‘Happy Hour’ to discuss the impact of COVID-19 on academic laboratories across the world.  Led by an impromptu panel of investigators (Camilla Forsberg, Trista North, Ross Levine, Len Zon, Kristina Kirshner, Momoko Yoshimoto-Kobayashi, Hanna Mikkola, Jennifer Trowbridge and Grant Rowe), we discussed the impact the global pandemic on our laboratory operations, our careers and those of trainees, and transitioning to work from home.  Katie Strang and Dovile Svirupskaite mediated the event and answered questions on the side in the parallel chat conversation.

We are looking forward to holding another virtual meeting in the coming weeks to touch on these issues and new challenges faced by investigators all over the world.

Here, we will present some highlights:

On laboratory operations
Most panelists faced a total shutdown of laboratory research, with access to facilities limited to ‘essential personnel’ necessary to maintain equipme…

Exploring Experimental Hematology: Tandem P-selectin glycoprotein ligand immunoglobulin (TSGL-Ig) prevents lung vaso-occlusion in sickle cell disease mice

Image
In this issue of Simply Blood, Derek Chan is exploring Experimental Hematology by highlighting and deconstructing one of the journal’s latest manuscripts on work led by first author Ravi Vats from the laboratory team of Dr. Prithu Sundd (Vats et al., 2020).

How do vaso-occlusive episodes occur in sickle cell disease?
The clinical course for patients with sickle cell disease (SCD) often involves recurrent and unpredictable episodes of painful vaso-occlusive episodes (VOEs) that may precipitate life-threatening sequelae.  While the molecular basis for SCD is well understood, the complex mechanisms underlying VOEs are not as well elucidated.

In these last two decades, several research groups have worked to characterize the contributions of both cellular and soluble components to the cascade of events leading to VOEs.  Notably, work using intravital microscopy has shown that the predominant in vivo interactions in the setting of a VOE occur between circulating sickled red blood cells, adhe…

Lab Spotlight: Liu Lab

Image
Each month, Simply Blood spotlights a lab focused on the research of basic hematology, immunology, stem cell research, cell and gene therapy, and other related aspects. Get to know these different labs around the world! This month, we are featuring the Liu Lab at the Institute of Zoology, Chinese Academy of Sciences in Beijing, China.


1. How long have you had your lab? 
11 years. I set up my lab in Institute of Zoology, Chinese Academy of Sciences in 2009.

2. How many members make up your lab?  Students/postdocs?
Currently, there are 17 members in my lab, including myself, 2 staff scientists and 14 graduate students.

3. What is the major research theme of your lab?
Our lab is focused on developmental hematopoiesis, primarily using zebrafish and mouse as animal models in addition to human cell cultures.

4. What is the most exciting project in your lab right now?

There are many exciting projects ongoing in my lab. The most fascinating project is to dissect the complex hematopoietic t…

Message from the President: Emmanuelle Passegué

Image
Dear ISEH members and stakeholders,

As you are undoubtedly aware, COVID-19 has been making headlines around the world for the past
few weeks and months. On behalf of the ISEH Board of Directors, I would like to extend our heartfelt wishes that you, your family and friends are well. 

Here, at ISEH, we are continuing to monitor the situation closely to determine whether any changes will occur for the ISEH 49th Annual Scientific Meeting in New York City on 20-23 August, 2020. The health and safety of our event attendees and partners is of the utmost importance and we will be following any recommended guidelines and best practices laid out by relevant health and safety entities as August approaches.

In response to the uncertainty we face due to the COVID-19 outbreaks around the world, ISEH will be extending our Call for Abstracts deadline to May 8 (previously April 13). Please note, submission of an abstract is FREE to ISEH members. We hope that you will continue to submit abstracts …