Showing posts from June, 2019

How to Review a Scientific Manuscript

Even in the era of open access and non-traditional forms of communication like social media, publication of research findings in peer-reviewed scientific journals remains the major way of disseminating our findings to the broader research community.  As such, appropriate peer-review is crucial for the critical review of new data before the findings are presented to the scientific public.  It seems simple enough right?  All of us read papers and think about what the results mean for our wok and for the field.  But we all have our own opinions about what makes a paper really exceptional.  When I read a paper I always think about why the authors chose to do a certain experiment a particular way, or why they didn’t follow up on this finding more.  So we all have an internal monologue, which serves as our own peer-review.  The people called upon by journals to review manuscripts essentially serve as gate-keepers to ensure rigorous and careful interpretation before the data are made public…

New Investigators: This Year’s ISEH NIC Invited Speaker is…

Every year at the ISEH meeting, the New Investigator Committee (NIC) invites one speaker to present in the New Investigator Award Session. For this year’s meeting in Brisbane, we have invited Marella de Bruijn PhD, Professor of Developmental Haematopoiesis at the University of Oxford. Marella completed her PhD at the University of Rotterdam in 1997 and went on to do postdoctoral training with Profs. Elaine Dzierzak and Nancy Speck, In 2003, Marella started her own lab at the Weatherall Institute of Molecular Medicine at Oxford, where she has focused on understanding the genetic regulation of developmental blood formation. Besides running her research laboratory, Marella has been heavily involved in training and mentorship at Oxford and within ISEH, and is this year’s organizer of the ISEH pre-meeting workshop. In preparation for her invited talk at ISEH, we caught up with Marella to find out more about her interests and her science.

Q&A with Marella de Bruijn:
Q1. How would you desc…

Lab Spotlight: McKinney-Freeman Lab

Each month, Simply Blood spotlights a lab focused on the research of basic hematology, immunology, stem cell research, cell and gene therapy, and other related aspects. Get to know these different labs around the world! This month, we are featuring the McKinney-Freeman Lab at St. Jude Children's Research Hospital.

1. How long have you had your lab? 
Almost nine years.

2. How many members make up your lab?  Students/postdocs?
Currently, my group consists of four postdoctoral fellows, two PhD students from the University of Tennessee Health Sciences Center, an international Master’s student from Paris Diderot University, an undergraduate from Rhodes College here in Memphis and a technician. I am currently looking to recruit a lab manager and multiple additional postdoctoral fellows.

3. What is the major research theme of your lab?

The major overarching theme of my lab is the basic biology of hematopoietic stem cells (HSCs). We are currently focused on deciphering novel molecular regul…